Helppp!! sort of virus attack

I kinda' need help, I had a sort of virus attack recently, that's solved, the thing is that every time I open Internet Explorer a page called Security Center appears and no matter haow many times I change the Homepage it still appears, and also, when I run my anti-spyware it detects a SpywareQuake_2.0 as a Infected folder, and it can't be quarentained, it is located on C:/WINDOWS/system32/1024 on my PC, i Have Windows XP Media Center, can anyone tell me how do I delete, clean or get rid off that thing?