you are unable to get into safemode......by rebooting and pressing F8?

Try this instead. start the computer and let windows open..

Close all open programs.
Click Start, Run and type MSCONFIG in the box and click OK
The System Configuration Utility appears, On the BOOT.INI tab, Check the "/SAFEBOOT" option, and then click OK and Restart your computer when prompted.
The computer restarts in Safe mode.
from safe mode you cab access the restore program and try to restore back to before what happened.

If it still doen't work then:
Turn off the system restore as virus loves to hide in the protected files.
Run your anti-virus program, your anti-spyware/malware programs


When you are finished with troubleshooting in Safe mode, open MSCONFIG again, on the BOOT.INI tab, uncheck "/SAFEBOOT" and click OK to restart your computer

Note******
By doing this in safe mode will help in speeding up the programs as a lot of the drivers and programs are not started in safemode so the virus is partially disabled.